My Ford F250 won't start, could someone help me understand how to fix it?

I hooked the battery up backwards one night and something made a crackling pop over towards the relays by the air filter (I think the wiper motor), then the solenoid let up a ton of smoke. I already checked the 3 pumps and they all still work, then checked the fuel rail and it doesn't spit gas like it did when I hooked the negative up to start check plug beside the relays and the air filter (which it started up when I connected those). I also checked the inertia switch which seemed good and I replaced a 14G fuse link that went from the the starter solenoid to the alternator, which already blew. While the trucks been sitting I went ahead and replaced the alternator because that was shot. If any of you know what the problem(s) might be, please write me some solutions on what I can do to make it run again. The truck has two tanks and it runs on gas.